Breakthroughs in artificial intelligence (AI) hold enormous potential as it can automate complex tasks and go even beyond human...
Better Medicines Through Bioinformatics
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Immuneering is applying bioinformatics to forge a new approach to drug discovery, develop transformative medicines and help others make the most of their data.
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Our commitment to rigor and reproducible data analysis is validated by a long track record of peer-reviewed publications. In collaboration with our partners in pharma and the scientific community, our research has been featured in a number of high-impact journals.
Oncolytic viruses (OVs) are a new class of cancer therapeutics. This review was undertaken to provide insight into the...
pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model
Huntington disease (HD), a devastating hereditary neurodegenerative disorder, is caused by an expansion of a CAG trinucleotide repeat that...
Endocrine-disrupting chemicals (EDCs) can interact with nuclear receptors, including estrogen receptor α (ERα) and androgen receptor (AR), to affect...
The recent global pandemic has placed a high priority on identifying drugs to prevent or lessen clinical infection of...
Although substantial concerns about the inflammatory effects of engineered nanomaterial (ENM) have been raised, experimentally assessing toxicity of various...
CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel...
Computational prediction models for assessing endocrine disrupting potential of chemicals
Endocrine disrupting chemicals (EDCs) mimic natural hormones and disrupt endocrine function. Humans and wildlife are exposed to EDCs might...
Huntington Disease (HD) is an incurable autosomal dominant neurodegenerative disorder driven by an expansion repeat giving rise to the...
When a small molecule binds to the androgen receptor (AR), a conformational change can occur which impacts subsequent binding...