Similarities and differences between variants called with human reference genome HG19 or HG38

By March 19, 2019April 23rd, 2021Publications
Reference genome selection is a prerequisite for successful analysis of next generation sequencing
(NGS) data. Current practice employs one of the two most recent human reference genome versions: HG19 or
HG38. To date, the impact of genome version on SNV identification has not been rigorously assessed.